A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication

• Olaf Isken,

  Affiliation Institute of Virology and Cell Biology, University of Lübeck, Germany

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• Ulrike Langerwisch,

  Affiliation Institute of Virology and Cell Biology, University of Lübeck, Germany

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• Vlastimil Jirasko,

  Affiliation Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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• Dirk Rehders,

  Affiliation Joint Laboratory for Structural Biology of Infection and Inflammation of the University of Hamburg and the University of Lübeck, DESY, Hamburg, Germany

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• Lars Redecke,

  Affiliation Joint Laboratory for Structural Biology of Infection and Inflammation of the University of Hamburg and the University of Lübeck, DESY, Hamburg, Germany

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• Harish Ramanathan,

  Affiliation Department of Microbial Pathogenesis, Yale University, New Haven, Connecticut, United States of America

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• Brett D. Lindenbach,

  Affiliation Department of Microbial Pathogenesis, Yale University, New Haven, Connecticut, United States of America

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• Ralf Bartenschlager,

  Affiliation Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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• Norbert Tautz

  * E-mail: tautz@vuz.uni-luebeck.de

  Affiliation Institute of Virology and Cell Biology, University of Lübeck, Germany

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