TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

Open Access

Peer-reviewed

Research Article

Peng Wang,

Affiliation Department of Immunology & Key Laboratory of Infection and Immunity of Shandong Province, the School of Medicine, Shandong University, Jinan, Shandong, China
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Wei Zhao,

Affiliation Department of Immunology & Key Laboratory of Infection and Immunity of Shandong Province, the School of Medicine, Shandong University, Jinan, Shandong, China
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Kai Zhao,

Affiliation Department of Immunology & Key Laboratory of Infection and Immunity of Shandong Province, the School of Medicine, Shandong University, Jinan, Shandong, China
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Lei Zhang,

Affiliation Department of Immunology & Key Laboratory of Infection and Immunity of Shandong Province, the School of Medicine, Shandong University, Jinan, Shandong, China
⨯
Chengjiang Gao

* E-mail: cgao@sdu.edu.cn

Affiliation Department of Immunology & Key Laboratory of Infection and Immunity of Shandong Province, the School of Medicine, Shandong University, Jinan, Shandong, China
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Transfection
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Plasmid construction
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Immunoprecipitation
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Small interfering RNA
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Macrophages
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Ubiquitination
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Vesicular stomatitis virus
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Phosphorylation
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