Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling

Rajeshree Pujari; Richard Hunte; Remy Thomas; Louise van der Weyden; Dan Rauch; Lee Ratner; Jennifer K. Nyborg; Juan Carlos Ramos; Yoshimi Takai; Noula Shembade

doi:10.1371/journal.ppat.1004721

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Peer-reviewed

Research Article

Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling

Rajeshree Pujari ,

Contributed equally to this work with: Rajeshree Pujari, Richard Hunte

Affiliation Department of Microbiology and Immunology, Viral Oncology Program, Sylvester Comprehensive Cancer Center, Miller School of Medicine, The University of Miami, Miami, Florida, United States of America
⨯
Richard Hunte ,

Contributed equally to this work with: Rajeshree Pujari, Richard Hunte

Affiliation Department of Microbiology and Immunology, Viral Oncology Program, Sylvester Comprehensive Cancer Center, Miller School of Medicine, The University of Miami, Miami, Florida, United States of America
⨯
Remy Thomas,

Affiliation Department of Microbiology and Immunology, Viral Oncology Program, Sylvester Comprehensive Cancer Center, Miller School of Medicine, The University of Miami, Miami, Florida, United States of America
⨯
Louise van der Weyden,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Dan Rauch,

Affiliation Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
⨯
Lee Ratner,

Affiliation Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
⨯
Jennifer K. Nyborg,

Affiliation Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Juan Carlos Ramos,

Affiliation Department of Medicine, Division of Hematology-Oncology, Viral Oncology Program, Sylvester Comprehensive Cancer Center, and Center for AIDS Research and Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Yoshimi Takai,

Affiliation Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Chuo-ku, Kobe, Japan
⨯
Noula Shembade

* E-mail: nshembade@med.miami.edu

Affiliation Department of Microbiology and Immunology, Viral Oncology Program, Sylvester Comprehensive Cancer Center, Miller School of Medicine, The University of Miami, Miami, Florida, United States of America
⨯

Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling

Rajeshree Pujari,
Richard Hunte,
Remy Thomas,
Louise van der Weyden,
Dan Rauch,
Lee Ratner,
Jennifer K. Nyborg,
Juan Carlos Ramos,
Yoshimi Takai,
Noula Shembade

Published: March 16, 2015
https://doi.org/10.1371/journal.ppat.1004721

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