XRN1 Stalling in the 5’ UTR of Hepatitis C Virus and Bovine Viral Diarrhea Virus Is Associated with Dysregulated Host mRNA Stability

Stephanie L. Moon; Jeffrey G. Blackinton; John R. Anderson; Mary K. Dozier; Benjamin J. T. Dodd; Jack D. Keene; Carol J. Wilusz; Shelton S. Bradrick; Jeffrey Wilusz

doi:10.1371/journal.ppat.1004708

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Open Access

Peer-reviewed

Research Article

XRN1 Stalling in the 5’ UTR of Hepatitis C Virus and Bovine Viral Diarrhea Virus Is Associated with Dysregulated Host mRNA Stability

Stephanie L. Moon,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Jeffrey G. Blackinton,

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
John R. Anderson,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Mary K. Dozier,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Benjamin J. T. Dodd,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Jack D. Keene,

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Carol J. Wilusz,

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯
Shelton S. Bradrick,

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Jeffrey Wilusz

* E-mail: jeffrey.wilusz@colostate.edu

Affiliation Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
⨯

XRN1 Stalling in the 5’ UTR of Hepatitis C Virus and Bovine Viral Diarrhea Virus Is Associated with Dysregulated Host mRNA Stability

Stephanie L. Moon,
Jeffrey G. Blackinton,
John R. Anderson,
Mary K. Dozier,
Benjamin J. T. Dodd,
Jack D. Keene,
Carol J. Wilusz,
Shelton S. Bradrick,
Jeffrey Wilusz

Published: March 6, 2015
https://doi.org/10.1371/journal.ppat.1004708

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Hepatitis C virus
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