Direct Binding of Retromer to Human Papillomavirus Type 16 Minor Capsid Protein L2 Mediates Endosome Exit during Viral Infection

Andreea Popa; Wei Zhang; Megan S. Harrison; Kylia Goodner; Teymur Kazakov; Edward C. Goodwin; Alex Lipovsky; Christopher G. Burd; Daniel DiMaio

doi:10.1371/journal.ppat.1004699

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Peer-reviewed

Research Article

Direct Binding of Retromer to Human Papillomavirus Type 16 Minor Capsid Protein L2 Mediates Endosome Exit during Viral Infection

Andreea Popa ,

Contributed equally to this work with: Andreea Popa, Wei Zhang

Current address: Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States of America

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
⨯
Wei Zhang ,

Contributed equally to this work with: Andreea Popa, Wei Zhang

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
⨯
Megan S. Harrison,

Affiliation Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut, United States of America
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Kylia Goodner,

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
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Teymur Kazakov,

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
⨯
Edward C. Goodwin,

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
⨯
Alex Lipovsky,

Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America
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Christopher G. Burd,

Affiliation Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut, United States of America
⨯
Daniel DiMaio

* E-mail: daniel.dimaio@yale.edu

Affiliations Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America, Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, United States of America, Department of Molecular Biophysics & Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America, Yale Cancer Center, New Haven, Connecticut, United States of America
⨯

Direct Binding of Retromer to Human Papillomavirus Type 16 Minor Capsid Protein L2 Mediates Endosome Exit during Viral Infection

Andreea Popa,
Wei Zhang,
Megan S. Harrison,
Kylia Goodner,
Teymur Kazakov,
Edward C. Goodwin,
Alex Lipovsky,
Christopher G. Burd,
Daniel DiMaio

Published: February 18, 2015
https://doi.org/10.1371/journal.ppat.1004699

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Endosomes
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Viral packaging
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Human papillomavirus infection
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HPV-16
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Sequence motif analysis
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