Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection

Maria Fernanda Pascutti; Sulima Geerman; Edith Slot; Klaas P. J. M. van Gisbergen; Louis Boon; Ramon Arens; Rene A. W van Lier; Monika C. Wolkers; Martijn A. Nolte

doi:10.1371/journal.ppat.1004675

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Peer-reviewed

Research Article

Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection

Maria Fernanda Pascutti,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Sulima Geerman,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Edith Slot,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Klaas P. J. M. van Gisbergen,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Louis Boon,

Affiliation Bioceros BV, Utrecht, The Netherlands
⨯
Ramon Arens,

Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
⨯
Rene A. W van Lier,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Monika C. Wolkers,

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯
Martijn A. Nolte

* E-mail: m.nolte@sanquin.nl

Affiliations Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
⨯

Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection

Maria Fernanda Pascutti,
Sulima Geerman,
Edith Slot,
Klaas P. J. M. van Gisbergen,
Louis Boon,
Ramon Arens,
Rene A. W van Lier,
Monika C. Wolkers,
Martijn A. Nolte

Published: March 4, 2015
https://doi.org/10.1371/journal.ppat.1004675

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