Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells

Annasara Lenman; A. Manuel Liaci; Yan Liu; Carin Årdahl; Anandi Rajan; Emma Nilsson; Will Bradford; Lisa Kaeshammer; Morris S. Jones; Lars Frängsmyr; Ten Feizi; Thilo Stehle; Niklas Arnberg

doi:10.1371/journal.ppat.1004657

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Open Access

Peer-reviewed

Research Article

Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells

Annasara Lenman ,

* E-mail: thilo.stehle@uni-tuebingen.de (TS, for structural biology); annasara.lenman@climi.umu.se (AL, for virology)

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯
A. Manuel Liaci,

Affiliation University of Tübingen, Interfaculty Institute of Biochemistry, Tübingen, Germany
⨯
Yan Liu,

Affiliation Glycosciences Laboratory, Department of Medicine, Imperial College London, London, United Kingdom
⨯
Carin Årdahl,

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯
Anandi Rajan,

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯
Emma Nilsson,

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯
Will Bradford,

Affiliation University of Tübingen, Interfaculty Institute of Biochemistry, Tübingen, Germany
⨯
Lisa Kaeshammer,

Affiliation University of Tübingen, Interfaculty Institute of Biochemistry, Tübingen, Germany
⨯
Morris S. Jones,

Affiliation Division of Infectious Diseases, Naval Medical Center, San Diego, California, United States of America
⨯
Lars Frängsmyr,

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯
Ten Feizi,

Affiliation Glycosciences Laboratory, Department of Medicine, Imperial College London, London, United Kingdom
⨯
Thilo Stehle ,

* E-mail: thilo.stehle@uni-tuebingen.de (TS, for structural biology); annasara.lenman@climi.umu.se (AL, for virology)

Affiliations University of Tübingen, Interfaculty Institute of Biochemistry, Tübingen, Germany, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Niklas Arnberg

Affiliation Division of Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden
⨯

Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells

Annasara Lenman,
A. Manuel Liaci,
Yan Liu,
Carin Årdahl,
Anandi Rajan,
Emma Nilsson,
Will Bradford,
Lisa Kaeshammer,
Morris S. Jones,
Lars Frängsmyr

Published: February 12, 2015
https://doi.org/10.1371/journal.ppat.1004657

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Sialic acids
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Cell binding
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Virions
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Binding analysis
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Vibrio cholerae
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Adenoviruses
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Flow cytometry
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Crystal structure
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