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Open Access
Peer-reviewed
Research Article
Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 Recipients
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Ling Yue ,
¶‡ LY, KJP and JB contributed equally to this work.
Affiliation Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
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Katja J. Pfafferott ,
¶‡ LY, KJP and JB contributed equally to this work.
Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Joshua Baalwa ,
¶‡ LY, KJP and JB contributed equally to this work.
Affiliation Department of Medicine, University of Alabama, Birmingham, Alabama, United States of America
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Karen Conrod,
Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Catherine C. Dong,
Affiliation Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
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Cecilia Chui,
Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Rong Rong,
Affiliation Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
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Daniel T. Claiborne,
Affiliation Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
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Jessica L. Prince,
Affiliation Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
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Jianming Tang,
Affiliation Department of Medicine, University of Alabama, Birmingham, Alabama, United States of America
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Ruy M. Ribeiro,
Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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Emmanuel Cormier,
Affiliation Human Immunology Laboratory, International AIDS Vaccine Initiative, London, United Kingdom
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Beatrice H. Hahn,
Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Alan S. Perelson,
Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
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George M. Shaw,
Affiliation Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Etienne Karita,
Affiliation Rwanda-Zambia HIV Research Project, Project San Francisco, Kigali, Rwanda
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Jill Gilmour,
Affiliation Human Immunology Laboratory, International AIDS Vaccine Initiative, London, United Kingdom
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Paul Goepfert,
Affiliation Department of Medicine, University of Alabama, Birmingham, Alabama, United States of America
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Cynthia A. Derdeyn,
Affiliations Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America
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Susan A. Allen,
Affiliation Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America
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Persephone Borrow ,
* E-mail: persephone.borrow@ndm.ox.ac.uk (PB); ehunte4@emory.edu (EH)
¶PB and EH also contributed equally to this work.
Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ - [ ... ],
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Eric Hunter
* E-mail: persephone.borrow@ndm.ox.ac.uk (PB); ehunte4@emory.edu (EH)
¶PB and EH also contributed equally to this work.
Affiliations Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America
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Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 Recipients
- Ling Yue,
- Katja J. Pfafferott,
- Joshua Baalwa,
- Karen Conrod,
- Catherine C. Dong,
- Cecilia Chui,
- Rong Rong,
- Daniel T. Claiborne,
- Jessica L. Prince,
- Jianming Tang
- Published: January 8, 2015
- https://doi.org/10.1371/journal.ppat.1004565