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Open Access
Peer-reviewed
Research Article
Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-Binding Site of HIV-1
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Laura E. McCoy ,
* E-mail: lmccoy@scripps.edu (LEM); r.weiss@ucl.ac.uk (RAW)
Current address: Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Lucy Rutten,
Affiliation QVQ B.V., Utrecht, The Netherlands
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Dan Frampton,
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Ian Anderson,
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Luke Granger,
Affiliation Department of Infectious Diseases, King's College London School of Medicine, Guy's Hospital, London, United Kingdom
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Rachael Bashford-Rogers,
Affiliation Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Gillian Dekkers,
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Nika M. Strokappe,
Affiliation QVQ B.V., Utrecht, The Netherlands
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Michael S. Seaman,
Affiliation Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Willie Koh,
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Vanina Grippo,
Affiliation Centro de Virología Animal, Instituto de Ciencia y Tecnología Dr. César Milstein, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
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Alexander Kliche,
Affiliation Institute of Medical Microbiology, University of Regensburg, Regensburg, Germany
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Theo Verrips,
Affiliation QVQ B.V., Utrecht, The Netherlands
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Paul Kellam,
Affiliation Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Ariberto Fassati,
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Robin A. Weiss
* E-mail: lmccoy@scripps.edu (LEM); r.weiss@ucl.ac.uk (RAW)
Affiliation Wohl Virion Centre and Medical Research Council (MRC) Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
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Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-Binding Site of HIV-1
- Laura E. McCoy,
- Lucy Rutten,
- Dan Frampton,
- Ian Anderson,
- Luke Granger,
- Rachael Bashford-Rogers,
- Gillian Dekkers,
- Nika M. Strokappe,
- Michael S. Seaman,
- Willie Koh
- Published: December 18, 2014
- https://doi.org/10.1371/journal.ppat.1004552