Plasma Membrane-Located Purine Nucleotide Transport Proteins Are Key Components for Host Exploitation by Microsporidian Intracellular Parasites

Eva Heinz; Christian Hacker; Paul Dean; John Mifsud; Alina V. Goldberg; Tom A. Williams; Sirintra Nakjang; Alison Gregory; Robert P. Hirt; John M. Lucocq; Edmund R. S. Kunji; T. Martin Embley

doi:10.1371/journal.ppat.1004547

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Open Access

Peer-reviewed

Research Article

Plasma Membrane-Located Purine Nucleotide Transport Proteins Are Key Components for Host Exploitation by Microsporidian Intracellular Parasites

Eva Heinz,

Affiliations Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom, Department of Microbiology, Monash University, Melbourne, Victoria, Australia, Victoria Bioinformatics Consortium, Monash University, Melbourne, Victoria, Australia
⨯
Christian Hacker,

Affiliation School of Medicine, University of St. Andrews, St. Andrews, United Kingdom
⨯
Paul Dean,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
John Mifsud,

Affiliation Medical Research Council, Mitochondrial Biology Unit, Cambridge, United Kingdom
⨯
Alina V. Goldberg,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Tom A. Williams,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Sirintra Nakjang,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Alison Gregory,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Robert P. Hirt,

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
John M. Lucocq ,

* E-mail: jml7@st-andrews.ac.uk (JML); edmund.kunji@mrc-mbu.cam.ac.uk (ERSK); Martin.Embley@ncl.ac.uk (TME)

Affiliation School of Medicine, University of St. Andrews, St. Andrews, United Kingdom
⨯
Edmund R. S. Kunji ,

* E-mail: jml7@st-andrews.ac.uk (JML); edmund.kunji@mrc-mbu.cam.ac.uk (ERSK); Martin.Embley@ncl.ac.uk (TME)

Affiliation Medical Research Council, Mitochondrial Biology Unit, Cambridge, United Kingdom
⨯
T. Martin Embley

* E-mail: jml7@st-andrews.ac.uk (JML); edmund.kunji@mrc-mbu.cam.ac.uk (ERSK); Martin.Embley@ncl.ac.uk (TME)

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯

Plasma Membrane-Located Purine Nucleotide Transport Proteins Are Key Components for Host Exploitation by Microsporidian Intracellular Parasites

Eva Heinz,
Christian Hacker,
Paul Dean,
John Mifsud,
Alina V. Goldberg,
Tom A. Williams,
Sirintra Nakjang,
Alison Gregory,
Robert P. Hirt,
John M. Lucocq

Published: December 4, 2014
https://doi.org/10.1371/journal.ppat.1004547

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Nucleotides
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Cell membranes
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Membrane proteins
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Purines
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Parasitic diseases
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