Anti-α4 Antibody Treatment Blocks Virus Traffic to the Brain and Gut Early, and Stabilizes CNS Injury Late in Infection

Jennifer H. Campbell; Eva-Maria Ratai; Patrick Autissier; David J. Nolan; Samantha Tse; Andrew D. Miller; R. Gilberto González; Marco Salemi; Tricia H. Burdo; Kenneth C. Williams

doi:10.1371/journal.ppat.1004533

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Peer-reviewed

Research Article

Anti-α4 Antibody Treatment Blocks Virus Traffic to the Brain and Gut Early, and Stabilizes CNS Injury Late in Infection

Jennifer H. Campbell,

Affiliation Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
⨯
Eva-Maria Ratai,

Affiliations Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Neuroscience, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Patrick Autissier,

Affiliation Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
⨯
David J. Nolan,

Affiliation Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, United States of America
⨯
Samantha Tse,

Affiliation Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
⨯
Andrew D. Miller,

Affiliation Department of Biomedical Sciences, Section of Anatomic Pathology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
⨯
R. Gilberto González,

Affiliation Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Marco Salemi,

Affiliation Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, United States of America
⨯
Tricia H. Burdo,

Affiliation Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
⨯
Kenneth C. Williams

* E-mail: kenneth.williams.3@bc.edu

Affiliation Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America
⨯

Anti-α4 Antibody Treatment Blocks Virus Traffic to the Brain and Gut Early, and Stabilizes CNS Injury Late in Infection

Jennifer H. Campbell,
Eva-Maria Ratai,
Patrick Autissier,
David J. Nolan,
Samantha Tse,
Andrew D. Miller,
R. Gilberto González,
Marco Salemi,
Tricia H. Burdo,
Kenneth C. Williams

Published: December 11, 2014
https://doi.org/10.1371/journal.ppat.1004533

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