IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

Silvia Moretti; Silvia Bozza; Vasilis Oikonomou; Giorgia Renga; Andrea Casagrande; Rossana G. Iannitti; Matteo Puccetti; Cecilia Garlanda; Soohyun Kim; Suzhao Li; Frank L. van de Veerdonk; Charles A. Dinarello; Luigina Romani

doi:10.1371/journal.ppat.1004462

Loading metrics

Open Access

Peer-reviewed

Research Article

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

Silvia Moretti ,

Contributed equally to this work with: Silvia Moretti, Silvia Bozza

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Silvia Bozza ,

Contributed equally to this work with: Silvia Moretti, Silvia Bozza

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Vasilis Oikonomou,

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Giorgia Renga,

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Andrea Casagrande,

Affiliations Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy, Istituto Superiore di Sanità, Roma, Italy
⨯
Rossana G. Iannitti,

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Matteo Puccetti,

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯
Cecilia Garlanda,

Affiliation Humanitas Clinical and Research Center, Rozzano, Milan, Italy
⨯
Soohyun Kim,

Affiliation Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Suzhao Li,

Affiliation Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Frank L. van de Veerdonk,

Affiliation Department of Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
⨯
Charles A. Dinarello,

Affiliations Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America, Department of Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
⨯
Luigina Romani

* E-mail: luigina.romani@unipg.it

Affiliation Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy
⨯

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

Silvia Moretti,
Silvia Bozza,
Vasilis Oikonomou,
Giorgia Renga,
Andrea Casagrande,
Rossana G. Iannitti,
Matteo Puccetti,
Cecilia Garlanda,
Soohyun Kim,
Suzhao Li

Published: November 6, 2014
https://doi.org/10.1371/journal.ppat.1004462

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Aspergillosis
Is the Subject Area "Aspergillosis" applicable to this article?

Thanks for your feedback.
Aspergillus
Is the Subject Area "Aspergillus" applicable to this article?

Thanks for your feedback.
Inflammasomes
Is the Subject Area "Inflammasomes" applicable to this article?

Thanks for your feedback.
Respiratory infections
Is the Subject Area "Respiratory infections" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.