Transgenic Analysis of the Leishmania MAP Kinase MPK10 Reveals an Auto-inhibitory Mechanism Crucial for Stage-Regulated Activity and Parasite Viability

• Mathieu Cayla ,

  Contributed equally to this work with: Mathieu Cayla, Najma Rachidi

  Affiliation Institut Pasteur and Centre National de la Recherche Scientifique URA 2581, Unité de Parasitologie Moléculaire et Signalisation, Paris, France

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• Najma Rachidi ,

  Contributed equally to this work with: Mathieu Cayla, Najma Rachidi

  Affiliation Institut Pasteur and Centre National de la Recherche Scientifique URA 2581, Unité de Parasitologie Moléculaire et Signalisation, Paris, France

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• Olivier Leclercq,

  Affiliation Institut Pasteur and Centre National de la Recherche Scientifique URA 2581, Unité de Parasitologie Moléculaire et Signalisation, Paris, France

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• Dirk Schmidt-Arras,

  Current address: Institute of Biochemistry, Christian-Albrechts-University Kiel, Kiel, Germany

  Affiliation Institut Pasteur and Centre National de la Recherche Scientifique URA 2581, Unité de Parasitologie Moléculaire et Signalisation, Paris, France

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• Heidi Rosenqvist,

  Affiliations Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland, Protein Research Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

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• Martin Wiese,

  Affiliation Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland

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• Gerald F. Späth

  * E-mail: gerald.spaeth@pasteur.fr

  Affiliation Institut Pasteur and Centre National de la Recherche Scientifique URA 2581, Unité de Parasitologie Moléculaire et Signalisation, Paris, France

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