Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity

• Melissa Starkey ,

  Contributed equally to this work with: Melissa Starkey, Francois Lepine, Damien Maura

  Current address: American College of Physicians, Philadelphia, Pennsylvania, United States of America

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Francois Lepine ,

  Contributed equally to this work with: Melissa Starkey, Francois Lepine, Damien Maura

  Affiliation INRS-Institut Armand Frappier, Laval, Québec, Canada

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• Damien Maura ,

  Contributed equally to this work with: Melissa Starkey, Francois Lepine, Damien Maura

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Arunava Bandyopadhaya,

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Biljana Lesic,

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Jianxin He,

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Tomoe Kitao,

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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• Valeria Righi,

  Affiliations NMR Surgical Laboratory, Department of Surgery, Massachusetts General and Shriners Hospitals, Harvard Medical School, Boston, Massachusetts, United States of America, Athinoula A. Martinos Center of Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Sylvain Milot,

  Affiliation INRS-Institut Armand Frappier, Laval, Québec, Canada

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• Aria Tzika,

  Affiliations NMR Surgical Laboratory, Department of Surgery, Massachusetts General and Shriners Hospitals, Harvard Medical School, Boston, Massachusetts, United States of America, Athinoula A. Martinos Center of Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Laurence Rahme

  * E-mail: rahme@molbio.mgh.harvard.edu

  Affiliations Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America, Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America

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