The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis

Jose M. Jimenez-Guardeño; Jose L. Nieto-Torres; Marta L. DeDiego; Jose A. Regla-Nava; Raul Fernandez-Delgado; Carlos Castaño-Rodriguez; Luis Enjuanes

doi:10.1371/journal.ppat.1004320

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Peer-reviewed

Research Article

The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis

Jose M. Jimenez-Guardeño,

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Jose L. Nieto-Torres,

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Marta L. DeDiego,

Current address: David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Jose A. Regla-Nava,

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Raul Fernandez-Delgado,

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Carlos Castaño-Rodriguez,

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯
Luis Enjuanes

* E-mail: L.Enjuanes@cnb.csic.es

Affiliation Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain
⨯

The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis

Jose M. Jimenez-Guardeño,
Jose L. Nieto-Torres,
Marta L. DeDiego,
Jose A. Regla-Nava,
Raul Fernandez-Delgado,
Carlos Castaño-Rodriguez,
Luis Enjuanes

Published: August 14, 2014
https://doi.org/10.1371/journal.ppat.1004320

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