Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver

• Juandy Jo ,

  Contributed equally to this work with: Juandy Jo, Anthony T. Tan

  Current address: Program of Immunology, Danone Nutricia Early Life Nutrition, Singapore

  Affiliation Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore

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• Anthony T. Tan ,

  Contributed equally to this work with: Juandy Jo, Anthony T. Tan

  Affiliation Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore

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• James E. Ussher,

  Current address: Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand

  Affiliation NIHR Biomedical Research Centre, John Radcliffe Hospital & Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

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• Elena Sandalova,

  Current address: Program of Immunology, Danone Nutricia Early Life Nutrition, Singapore

  Affiliation Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore

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• Xin-Zi Tang,

  Affiliation Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore

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• Alfonso Tan-Garcia,

  Affiliation Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore

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• Natalie To,

  Affiliation Institute of Cell and Molecular Science, Barts and the London School of Medicine & Dentistry, London, United Kingdom

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• Michelle Hong,

  Affiliation Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore

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• Adeline Chia,

  Affiliation Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore

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• Upkar S. Gill,

  Affiliation Institute of Cell and Molecular Science, Barts and the London School of Medicine & Dentistry, London, United Kingdom

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• Patrick T. Kennedy,

  Affiliation Institute of Cell and Molecular Science, Barts and the London School of Medicine & Dentistry, London, United Kingdom

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• Kai Chah Tan,

  Affiliation Asian American Liver Centre, Singapore

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• Kang Hoe Lee,

  Affiliation Asian American Liver Centre, Singapore

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• Gennaro De Libero,

  Affiliation Experimental Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland

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• Adam J. Gehring,

  Current address: St. Louis University School of Medicine, St. Louis, Missouri, United States of America

  Affiliation Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore

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• Christian B. Willberg,

  Affiliation NIHR Biomedical Research Centre, John Radcliffe Hospital & Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

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• Paul Klenerman,

  Affiliation NIHR Biomedical Research Centre, John Radcliffe Hospital & Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom

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•  [ ... ],
• Antonio Bertoletti

  * E-mail: antonio@duke-nus.edu.sg

  Affiliations Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, Agency of Science Technology and Research (A*STAR), Singapore, Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, School of Immunity and Infection, College of Medical and Dental Science, University of Birmingham, Edgbaston Birmingham, United Kingdom

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