IscR Is Essential for Yersinia pseudotuberculosis Type III Secretion and Virulence

Halie K. Miller; Laura Kwuan; Leah Schwiesow; David L. Bernick; Erin Mettert; Hector A. Ramirez; James M. Ragle; Patricia P. Chan; Patricia J. Kiley; Todd M. Lowe; Victoria Auerbuch

doi:10.1371/journal.ppat.1004194

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Open Access

Peer-reviewed

Research Article

IscR Is Essential for Yersinia pseudotuberculosis Type III Secretion and Virulence

Halie K. Miller,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Laura Kwuan,

Current address: Quality Control Microbiology, Genentech Inc., South San Francisco, California, United States of America

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Leah Schwiesow,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
David L. Bernick,

Affiliation Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Erin Mettert,

Affiliation Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Hector A. Ramirez,

Current address: Infectious Diseases Department of Roche Molecular Systems, Inc., Pleasanton, California, United States of America

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
James M. Ragle,

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Patricia P. Chan,

Current address: Maverix Biomics, Inc., San Mateo, California, United States of America

Affiliation Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Patricia J. Kiley,

Affiliation Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Todd M. Lowe,

Affiliation Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Victoria Auerbuch

* E-mail: vastone@ucsc.edu

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯

IscR Is Essential for Yersinia pseudotuberculosis Type III Secretion and Virulence

Halie K. Miller,
Laura Kwuan,
Leah Schwiesow,
David L. Bernick,
Erin Mettert,
Hector A. Ramirez,
James M. Ragle,
Patricia P. Chan,
Patricia J. Kiley,
Todd M. Lowe

Published: June 12, 2014
https://doi.org/10.1371/journal.ppat.1004194

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Yersinia pseudotuberculosis
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Secretion systems
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Operons
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Chaperone proteins
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Gene regulation
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Secretion
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Transcriptional control
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Gene expression
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