The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Luis Solans; Jesús Gonzalo-Asensio; Claudia Sala; Andrej Benjak; Swapna Uplekar; Jacques Rougemont; Christophe Guilhot; Wladimir Malaga; Carlos Martín; Stewart T. Cole

doi:10.1371/journal.ppat.1004183

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Peer-reviewed

Research Article

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Luis Solans ,

Contributed equally to this work with: Luis Solans, Jesús Gonzalo-Asensio, Claudia Sala

Affiliations Grupo de Genética de Micobacterias, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain
⨯
Jesús Gonzalo-Asensio ,

Contributed equally to this work with: Luis Solans, Jesús Gonzalo-Asensio, Claudia Sala

Affiliations CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain, Servicio de Microbiología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain
⨯
Claudia Sala ,

Contributed equally to this work with: Luis Solans, Jesús Gonzalo-Asensio, Claudia Sala

Affiliation Ecole Polytechnique Fédérale de Lausanne, Global Health Institute, Station 19, Lausanne, Switzerland
⨯
Andrej Benjak,

Affiliation Ecole Polytechnique Fédérale de Lausanne, Global Health Institute, Station 19, Lausanne, Switzerland
⨯
Swapna Uplekar,

Affiliation Ecole Polytechnique Fédérale de Lausanne, Global Health Institute, Station 19, Lausanne, Switzerland
⨯
Jacques Rougemont,

Affiliation Ecole Polytechnique Fédérale de Lausanne, Bioinformatics and Biostatistics Core Facility, Station 19, Lausanne, Switzerland
⨯
Christophe Guilhot,

Affiliations Département Mécanismes Moléculaires des Infections Mycobactériennes, Institut de Pharmacologie et Biologie Structural, CNRS, Toulouse, France, Université Paul Sabatier, Toulouse, France
⨯
Wladimir Malaga,

Affiliations Département Mécanismes Moléculaires des Infections Mycobactériennes, Institut de Pharmacologie et Biologie Structural, CNRS, Toulouse, France, Université Paul Sabatier, Toulouse, France
⨯
Carlos Martín,

Affiliations Grupo de Genética de Micobacterias, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain, Servicio de Microbiología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain
⨯
Stewart T. Cole

* E-mail: stewart.cole@epfl.ch

Affiliation Ecole Polytechnique Fédérale de Lausanne, Global Health Institute, Station 19, Lausanne, Switzerland
⨯

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Luis Solans,
Jesús Gonzalo-Asensio,
Claudia Sala,
Andrej Benjak,
Swapna Uplekar,
Jacques Rougemont,
Christophe Guilhot,
Wladimir Malaga,
Carlos Martín,
Stewart T. Cole

Published: May 29, 2014
https://doi.org/10.1371/journal.ppat.1004183

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Mycobacterium tuberculosis
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Non-coding RNA
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Transcriptional control
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Immunoprecipitation
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Secretion systems
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Gene expression
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