The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification

Read Pukkila-Worley; Rhonda L. Feinbaum; Deborah L. McEwan; Annie L. Conery; Frederick M. Ausubel

doi:10.1371/journal.ppat.1004143

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Research Article

The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification

Read Pukkila-Worley ,

Contributed equally to this work with: Read Pukkila-Worley, Rhonda L. Feinbaum

* E-mail: rpukkilaworley@partners.org

Affiliations Division of Infectious Diseases; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Molecular Biology; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Genetics; Harvard Medical School; Boston, Massachusetts, United States of America
⨯
Rhonda L. Feinbaum ,

Contributed equally to this work with: Read Pukkila-Worley, Rhonda L. Feinbaum

Affiliations Department of Molecular Biology; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Genetics; Harvard Medical School; Boston, Massachusetts, United States of America
⨯
Deborah L. McEwan,

Affiliations Department of Molecular Biology; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Genetics; Harvard Medical School; Boston, Massachusetts, United States of America
⨯
Annie L. Conery,

Affiliations Department of Molecular Biology; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Genetics; Harvard Medical School; Boston, Massachusetts, United States of America
⨯
Frederick M. Ausubel

Affiliations Department of Molecular Biology; Massachusetts General Hospital; Harvard Medical School; Boston, Massachusetts, United States of America, Department of Genetics; Harvard Medical School; Boston, Massachusetts, United States of America
⨯

The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification

Read Pukkila-Worley,
Rhonda L. Feinbaum,
Deborah L. McEwan,
Annie L. Conery,
Frederick M. Ausubel

Published: May 29, 2014
https://doi.org/10.1371/journal.ppat.1004143

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Immune response
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RNA interference
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