Squalene Synthase As a Target for Chagas Disease Therapeutics

• Na Shang ,

  Contributed equally to this work with: Na Shang, Qian Li, Tzu-Ping Ko

  Affiliations Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

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• Qian Li ,

  Contributed equally to this work with: Na Shang, Qian Li, Tzu-Ping Ko

  Affiliations Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

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• Tzu-Ping Ko ,

  Contributed equally to this work with: Na Shang, Qian Li, Tzu-Ping Ko

  Affiliations Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

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• Hsiu-Chien Chan,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Jikun Li,

  Affiliation Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

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• Yingying Zheng,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Chun-Hsiang Huang,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Feifei Ren,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Chun-Chi Chen,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Zhen Zhu,

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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• Melina Galizzi,

  Affiliation Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

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• Zhu-Hong Li,

  Affiliation Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

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• Carlos A. Rodrigues-Poveda,

  Affiliation Instituto de Parasitología y Biomedicina “Lopez-Neyra”, Consejo Superior de Investigaciones Cientificas, Granada, Spain

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• Dolores Gonzalez-Pacanowska,

  Affiliation Instituto de Parasitología y Biomedicina “Lopez-Neyra”, Consejo Superior de Investigaciones Cientificas, Granada, Spain

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• Phercyles Veiga-Santos,

  Affiliations Laboratório de Ultraestrutura Celular Hertha Meyer, CCS, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro, Brazil, Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, Brazil, Diretoria de Programa, Instituto Nacional de Metrologia, Normalização e Qualidade Industrial–INMETRO, Duque de Caxias, Rio de Janeiro, Brazil

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• Tecia Maria Ulisses de Carvalho,

  Affiliations Laboratório de Ultraestrutura Celular Hertha Meyer, CCS, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro, Brazil, Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, Brazil, Diretoria de Programa, Instituto Nacional de Metrologia, Normalização e Qualidade Industrial–INMETRO, Duque de Caxias, Rio de Janeiro, Brazil

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• Wanderley de Souza,

  Affiliations Laboratório de Ultraestrutura Celular Hertha Meyer, CCS, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro, Brazil, Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, Brazil, Diretoria de Programa, Instituto Nacional de Metrologia, Normalização e Qualidade Industrial–INMETRO, Duque de Caxias, Rio de Janeiro, Brazil

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• Julio A. Urbina,

  Affiliation Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela

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• Andrew H.-J. Wang,

  Affiliation Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

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• Roberto Docampo,

  Affiliation Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

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• Kai Li,

  Affiliation Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

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• Yi-Liang Liu,

  Affiliation Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

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• Eric Oldfield ,

  * E-mail: eoldfiel@illinois.edu (EO); guo_rt@tib.cas.cn (RTG)

  Affiliations Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

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•  [ ... ],
• Rey-Ting Guo

  * E-mail: eoldfiel@illinois.edu (EO); guo_rt@tib.cas.cn (RTG)

  Affiliation Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

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