A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity

• Hangfei Qi,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• C. Anders Olson,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• Nicholas C. Wu,

  Affiliation The Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Ruian Ke,

  Affiliation Department of Ecology and Evolutionary Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Claude Loverdo,

  Affiliation Department of Ecology and Evolutionary Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Virginia Chu,

  Affiliation Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Shawna Truong,

  Affiliation Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Roland Remenyi,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• Zugen Chen,

  Affiliation Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America

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• Yushen Du,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• Sheng-Yao Su,

  Affiliations Institute of Information Science, Academia Sinica, Taipei, Taiwan, Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan

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• Laith Q. Al-Mawsawi,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• Ting-Ting Wu,

  Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America

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• Shu-Hua Chen,

  Affiliation Institute of Information Science, Academia Sinica, Taipei, Taiwan

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• Chung-Yen Lin,

  Affiliation Institute of Information Science, Academia Sinica, Taipei, Taiwan

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• Weidong Zhong,

  Affiliation Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

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• James O. Lloyd-Smith,

  Affiliations Department of Ecology and Evolutionary Biology, University of California Los Angeles, Los Angeles, California, United States of America, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

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•  [ ... ],
• Ren Sun

  * E-mail: rsun@mednet.ucla.edu

  Affiliations Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America, The Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

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