Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

Christopher D. Dupont; David A. Christian; Elizabeth M. Selleck; Marion Pepper; Michael Leney-Greene; Gretchen Harms Pritchard; Anita A. Koshy; Sagie Wagage; Morgan A. Reuter; L. David Sibley; Michael R. Betts; Christopher A. Hunter

doi:10.1371/journal.ppat.1004047

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Open Access

Peer-reviewed

Research Article

Parasite Fate and Involvement of Infected Cells in the Induction of CD4⁺ and CD8⁺ T Cell Responses to Toxoplasma gondii

Christopher D. Dupont,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
David A. Christian,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Elizabeth M. Selleck,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Marion Pepper,

Affiliation Department of Immunology, University of Washington, Seattle, Washington, United States of America
⨯
Michael Leney-Greene,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Gretchen Harms Pritchard,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Anita A. Koshy,

Affiliation Department of Neurology, University of Arizona, Tucson, Arizona, United States of America
⨯
Sagie Wagage,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Morgan A. Reuter,

Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
L. David Sibley,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Michael R. Betts,

Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Christopher A. Hunter

* E-mail: chunter@vet.upenn.edu

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Parasite Fate and Involvement of Infected Cells in the Induction of CD4⁺ and CD8⁺ T Cell Responses to Toxoplasma gondii

Christopher D. Dupont,
David A. Christian,
Elizabeth M. Selleck,
Marion Pepper,
Michael Leney-Greene,
Gretchen Harms Pritchard,
Anita A. Koshy,
Sagie Wagage,
Morgan A. Reuter,
L. David Sibley

Published: April 10, 2014
https://doi.org/10.1371/journal.ppat.1004047

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Parasitic diseases
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T cells
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Cytotoxic T cells
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Toxoplasma gondii
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