HMGB1-Promoted and TLR2/4-Dependent NK Cell Maturation and Activation Take Part in Rotavirus-Induced Murine Biliary Atresia

Yinrong Qiu; Jixin Yang; Wenmei Wang; Wentao Zhao; Fei Peng; Ying Xiang; Gang Chen; Tao Chen; Chengwei Chai; Shuaiyu Zheng; Daniel J. Watkins; Jiexiong Feng

doi:10.1371/journal.ppat.1004011

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Open Access

Peer-reviewed

Research Article

HMGB1-Promoted and TLR2/4-Dependent NK Cell Maturation and Activation Take Part in Rotavirus-Induced Murine Biliary Atresia

Yinrong Qiu ,

Contributed equally to this work with: Yinrong Qiu, Jixin Yang

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Jixin Yang ,

Contributed equally to this work with: Yinrong Qiu, Jixin Yang

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Wenmei Wang,

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Wentao Zhao,

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Fei Peng,

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Ying Xiang,

Affiliation Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Gang Chen,

Affiliation Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Tao Chen,

Affiliation Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Chengwei Chai,

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Shuaiyu Zheng,

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Daniel J. Watkins,

Affiliation Department of Surgery, Wayne State University, Detroit, Michigan, United States of America
⨯
Jiexiong Feng

* E-mail: fengjiexiong@126.com

Affiliation Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯

HMGB1-Promoted and TLR2/4-Dependent NK Cell Maturation and Activation Take Part in Rotavirus-Induced Murine Biliary Atresia

Yinrong Qiu,
Jixin Yang,
Wenmei Wang,
Wentao Zhao,
Fei Peng,
Ying Xiang,
Gang Chen,
Tao Chen,
Chengwei Chai,
Shuaiyu Zheng

Published: March 20, 2014
https://doi.org/10.1371/journal.ppat.1004011

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NK cells
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Mouse models
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Bile ducts
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