Activation of HIV-1 from Latent Infection via Synergy of RUNX1 Inhibitor Ro5-3335 and SAHA

Zachary Klase; Venkat S. R. K. Yedavalli; Laurent Houzet; Molly Perkins; Frank Maldarelli; Jason Brenchley; Klaus Strebel; Paul Liu; Kuan-Teh Jeang

doi:10.1371/journal.ppat.1003997

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Open Access

Peer-reviewed

Research Article

Activation of HIV-1 from Latent Infection via Synergy of RUNX1 Inhibitor Ro5-3335 and SAHA

Zachary Klase ,

* E-mail: klaseza@niaid.nih.gov

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Venkat S. R. K. Yedavalli,

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Laurent Houzet,

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Molly Perkins,

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Frank Maldarelli,

Affiliation Host Virus Interaction Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jason Brenchley,

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Klaus Strebel,

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Paul Liu,

Affiliation Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kuan-Teh Jeang †

† Deceased.

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Activation of HIV-1 from Latent Infection via Synergy of RUNX1 Inhibitor Ro5-3335 and SAHA

Zachary Klase,
Venkat S. R. K. Yedavalli,
Laurent Houzet,
Molly Perkins,
Frank Maldarelli,
Jason Brenchley,
Klaus Strebel,
Paul Liu,
Kuan-Teh Jeang

Published: March 20, 2014
https://doi.org/10.1371/journal.ppat.1003997

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