Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

• Peihong Dai ,

  Contributed equally to this work with: Peihong Dai, Weiyi Wang

  Affiliations Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Weiyi Wang ,

  Contributed equally to this work with: Peihong Dai, Weiyi Wang

  Affiliation Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Hua Cao,

  Affiliations Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Francesca Avogadri,

  Affiliation Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Lianpan Dai,

  Affiliation Institute for Virology, Düsseldorf University Hospital, Heinrich-Heine-University, Düsseldorf, Germany

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• Ingo Drexler,

  Affiliation Institute for Virology, Düsseldorf University Hospital, Heinrich-Heine-University, Düsseldorf, Germany

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• Johanna A. Joyce,

  Affiliation Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Xiao-Dong Li,

  Affiliation Department of Molecular Biology, University of Texas, Southwestern Medical Center, Dallas, Texas, United States of America

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• Zhijian Chen,

  Affiliation Department of Molecular Biology, University of Texas, Southwestern Medical Center, Dallas, Texas, United States of America

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• Taha Merghoub,

  Affiliation Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Stewart Shuman,

  Affiliations Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Lucille Castori Center for Microbes, Inflammation and Cancer, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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• Liang Deng

  * E-mail: dengl@mskcc.org

  Affiliations Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Lucille Castori Center for Microbes, Inflammation and Cancer, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

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