ChIP-Seq and RNA-Seq Reveal an AmrZ-Mediated Mechanism for Cyclic di-GMP Synthesis and Biofilm Development by Pseudomonas aeruginosa

• Christopher J. Jones,

  Affiliations Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America, Department of Infection and Immunity and Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America

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• David Newsom,

  Affiliation Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America

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• Benjamin Kelly,

  Affiliation Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America

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• Yasuhiko Irie,

  Affiliation Department of Biology & Biochemistry, University of Bath, Claverton Down, Bath, United Kingdom

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• Laura K. Jennings,

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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• Binjie Xu,

  Affiliation Department of Microbiology, Ohio State University, Columbus, Ohio, United States of America

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• Dominique H. Limoli,

  Affiliation Department of Infection and Immunity and Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America

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• Joe J. Harrison,

  Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

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• Matthew R. Parsek,

  Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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• Peter White,

  Affiliation Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America

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• Daniel J. Wozniak

  * E-mail: daniel.wozniak@osumc.edu

  Affiliations Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America, Department of Microbiology, Ohio State University, Columbus, Ohio, United States of America

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