The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

Yi-Shan Chen; Robert J. Bastidas; Hector A. Saka; Victoria K. Carpenter; Kristian L. Richards; Gregory V. Plano; Raphael H. Valdivia

doi:10.1371/journal.ppat.1003954

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Research Article

The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

Yi-Shan Chen,

Affiliations Department of Molecular Genetics and Microbiology and Center for Microbial Pathogenesis, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America
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Robert J. Bastidas,

Affiliation Department of Molecular Genetics and Microbiology and Center for Microbial Pathogenesis, Duke University Medical Center, Durham, North Carolina, United States of America
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Hector A. Saka,

Affiliation Department of Molecular Genetics and Microbiology and Center for Microbial Pathogenesis, Duke University Medical Center, Durham, North Carolina, United States of America
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Victoria K. Carpenter,

Affiliation Department of Molecular Genetics and Microbiology and Center for Microbial Pathogenesis, Duke University Medical Center, Durham, North Carolina, United States of America
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Kristian L. Richards,

Affiliation Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
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Gregory V. Plano,

Affiliation Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
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Raphael H. Valdivia

* E-mail: Raphael.valdivia@duke.edu

Affiliation Department of Molecular Genetics and Microbiology and Center for Microbial Pathogenesis, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

Yi-Shan Chen,
Robert J. Bastidas,
Hector A. Saka,
Victoria K. Carpenter,
Kristian L. Richards,
Gregory V. Plano,
Raphael H. Valdivia

Published: February 20, 2014
https://doi.org/10.1371/journal.ppat.1003954

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05 Mar 2014
18:54 GMT
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Correction Posted by YiShanChen on 05 Mar 2014 at 18:54 GMT

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Chlamydia infection
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Chlamydia trachomatis
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Phosphorylation
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Chlamydia
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Immunoprecipitation
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HeLa cells
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Secretion
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