Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcδ

• Shiho Suzuki,

  Affiliations Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Division of Bacterial Infection Biology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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• Luigi Franchi,

  Affiliations Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Lycera Corp., Ann Arbor, Michigan, United States of America

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• Yuan He,

  Affiliation Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Raul Muñoz-Planillo,

  Affiliation Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Hitomi Mimuro,

  Affiliation Division of Bacteriology, Department of Infectious Diseases Control, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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• Toshihiko Suzuki,

  Affiliation Department of Molecular Bacteriology and Immunology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan

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• Chihiro Sasakawa,

  Affiliations Division of Bacterial Infection Biology, Institute of Medical Science, University of Tokyo, Tokyo, Japan, Nippon Institute for Biological Science, Tokyo, Japan

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• Gabriel Núñez

  * E-mail: gabriel.nunez@umich.edu

  Affiliation Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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