Foxp3+ Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice

Birte Blankenhaus; Martina Reitz; Yannick Brenz; Marie-Luise Eschbach; Wiebke Hartmann; Irma Haben; Tim Sparwasser; Jochen Huehn; Anja Kühl; Thorsten B. Feyerabend; Hans-Reimer Rodewald; Minka Breloer

doi:10.1371/journal.ppat.1003913

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Research Article

Foxp3⁺ Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice

Birte Blankenhaus ,

Contributed equally to this work with: Birte Blankenhaus, Martina Reitz

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Martina Reitz ,

Contributed equally to this work with: Birte Blankenhaus, Martina Reitz

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Yannick Brenz,

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Marie-Luise Eschbach,

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Wiebke Hartmann,

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Irma Haben,

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯
Tim Sparwasser,

Affiliation Institute of Infection Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Helmholtz Centre for Infection Research Braunschweig and the Hanover Medical School, Hanover, Germany
⨯
Jochen Huehn,

Affiliation Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯
Anja Kühl,

Affiliation Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité-Campus Benjamin Franklin, Berlin, Germany
⨯
Thorsten B. Feyerabend,

Affiliation Division for Cellular Immunology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
⨯
Hans-Reimer Rodewald,

Affiliation Division for Cellular Immunology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
⨯
Minka Breloer

* E-mail: breloer@bnitm.de

Affiliation Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
⨯

Foxp3⁺ Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice

Birte Blankenhaus,
Martina Reitz,
Yannick Brenz,
Marie-Luise Eschbach,
Wiebke Hartmann,
Irma Haben,
Tim Sparwasser,
Jochen Huehn,
Anja Kühl,
Thorsten B. Feyerabend

Published: February 6, 2014
https://doi.org/10.1371/journal.ppat.1003913

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09 Apr 2014
23:17 GMT
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Correction to the Funding Statement Posted by PLOS_Pathogens on 09 Apr 2014 at 23:17 GMT

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Parasitic intestinal diseases
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Small intestine
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