RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation

Meleri Jones; Inga R. Dry; Dan Frampton; Manuraj Singh; Ravinder K. Kanda; Michael B. Yee; Paul Kellam; Michael Hollinshead; Paul R. Kinchington; Edel A. O'Toole; Judith Breuer

doi:10.1371/journal.ppat.1003896

Loading metrics

Open Access

Peer-reviewed

Research Article

RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation

Meleri Jones ,

Contributed equally to this work with: Meleri Jones, Inga R. Dry, Dan Frampton

* E-mail: meleri.jones@ucl.ac.uk

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Inga R. Dry ,

Contributed equally to this work with: Meleri Jones, Inga R. Dry, Dan Frampton

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Dan Frampton ,

Contributed equally to this work with: Meleri Jones, Inga R. Dry, Dan Frampton

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Manuraj Singh,

Affiliation Centre for Cutaneous Research, QMUL, London, United Kingdom
⨯
Ravinder K. Kanda,

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Michael B. Yee,

Affiliation Department of Ophthalmology and of Molecular Microbiology and Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Paul Kellam,

Affiliations Division of Infection and Immunity, University College London, London, United Kingdom, Virus Genomics Team, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
⨯
Michael Hollinshead,

Affiliation Section of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Paul R. Kinchington,

Affiliation Department of Ophthalmology and of Molecular Microbiology and Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Edel A. O'Toole,

Affiliation Centre for Cutaneous Research, QMUL, London, United Kingdom
⨯
Judith Breuer

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯

RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation

Meleri Jones,
Inga R. Dry,
Dan Frampton,
Manuraj Singh,
Ravinder K. Kanda,
Michael B. Yee,
Paul Kellam,
Michael Hollinshead,
Paul R. Kinchington,
Edel A. O'Toole

Published: January 30, 2014
https://doi.org/10.1371/journal.ppat.1003896

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Keratinocytes
Is the Subject Area "Keratinocytes" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Epidermis
Is the Subject Area "Epidermis" applicable to this article?

Thanks for your feedback.
Viral gene expression
Is the Subject Area "Viral gene expression" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Skin infections
Is the Subject Area "Skin infections" applicable to this article?

Thanks for your feedback.
Transcriptome analysis
Is the Subject Area "Transcriptome analysis" applicable to this article?

Thanks for your feedback.