Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Elodie Ramond; Gael Gesbert; Mélanie Rigard; Julien Dairou; Marion Dupuis; Iharilalao Dubail; Karin Meibom; Thomas Henry; Monique Barel; Alain Charbit

doi:10.1371/journal.ppat.1003893

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Peer-reviewed

Research Article

Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Elodie Ramond,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Gael Gesbert,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Mélanie Rigard,

Affiliations Centre international de recherche en infectiologie, Université de Lyon, Lyon, France, Bacterial Pathogenesis and Innate Immunity Laboratory, INSERM U851 “Immunity, Infection and Vaccination”, Lyon, France
⨯
Julien Dairou,

Affiliation Platform “Bioprofiler” Université Paris Diderot, Paris, France
⨯
Marion Dupuis,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Iharilalao Dubail,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Karin Meibom,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Thomas Henry,

Affiliations Centre international de recherche en infectiologie, Université de Lyon, Lyon, France, Bacterial Pathogenesis and Innate Immunity Laboratory, INSERM U851 “Immunity, Infection and Vaccination”, Lyon, France
⨯
Monique Barel,

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯
Alain Charbit

* E-mail: alain.charbit@inserm.fr

Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, INSERM, U1002, Unité de Pathogénie des Infections Systémiques, Paris, France
⨯

Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Elodie Ramond,
Gael Gesbert,
Mélanie Rigard,
Julien Dairou,
Marion Dupuis,
Iharilalao Dubail,
Karin Meibom,
Thomas Henry,
Monique Barel,
Alain Charbit

Published: January 16, 2014
https://doi.org/10.1371/journal.ppat.1003893

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Francisella
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Oxidative stress
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Francisella tularensis
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