The CD8-Derived Chemokine XCL1/Lymphotactin Is a Conformation-Dependent, Broad-Spectrum Inhibitor of HIV-1

Christina Guzzo; Jamie Fox; Yin Lin; Huiyi Miao; Raffaello Cimbro; Brian F. Volkman; Anthony S. Fauci; Paolo Lusso

doi:10.1371/journal.ppat.1003852

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Peer-reviewed

Research Article

The CD8-Derived Chemokine XCL1/Lymphotactin Is a Conformation-Dependent, Broad-Spectrum Inhibitor of HIV-1

Christina Guzzo,

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jamie Fox,

Affiliation Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Yin Lin,

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Huiyi Miao,

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Raffaello Cimbro,

Current address: Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Brian F. Volkman,

Affiliation Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Anthony S. Fauci,

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Paolo Lusso

* E-mail: plusso@niaid.nih.gov

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

The CD8-Derived Chemokine XCL1/Lymphotactin Is a Conformation-Dependent, Broad-Spectrum Inhibitor of HIV-1

Christina Guzzo,
Jamie Fox,
Yin Lin,
Huiyi Miao,
Raffaello Cimbro,
Brian F. Volkman,
Anthony S. Fauci,
Paolo Lusso

Published: December 26, 2013
https://doi.org/10.1371/journal.ppat.1003852

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