Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

Luis Muniz-Feliciano; Jennifer Van Grol; Jose-Andres C. Portillo; Lloyd Liew; Bing Liu; Cathleen R. Carlin; Vern B. Carruthers; Stephen Matthews; Carlos S. Subauste

doi:10.1371/journal.ppat.1003809

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Peer-reviewed

Research Article

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

Luis Muniz-Feliciano,

Affiliations Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
⨯
Jennifer Van Grol,

Affiliations Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
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Jose-Andres C. Portillo,

Affiliation Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
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Lloyd Liew,

Affiliation Division of Molecular Biosciences, Imperial College London, London, United Kingdom
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Bing Liu,

Affiliation Division of Molecular Biosciences, Imperial College London, London, United Kingdom
⨯
Cathleen R. Carlin,

Affiliation Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
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Vern B. Carruthers,

Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Stephen Matthews,

Affiliation Division of Molecular Biosciences, Imperial College London, London, United Kingdom
⨯
Carlos S. Subauste

* E-mail: carlos.subauste@case.edu

Affiliations Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America, Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

Luis Muniz-Feliciano,
Jennifer Van Grol,
Jose-Andres C. Portillo,
Lloyd Liew,
Bing Liu,
Cathleen R. Carlin,
Vern B. Carruthers,
Stephen Matthews,
Carlos S. Subauste

Published: December 19, 2013
https://doi.org/10.1371/journal.ppat.1003809

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Autophagic cell death
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