IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation

Qiliang Cai; Shuvomoy Banerjee; Amanda Cervini; Jie Lu; Andrew D. Hislop; Richard Dzeng; Erle S. Robertson

doi:10.1371/journal.ppat.1003751

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Peer-reviewed

Research Article

IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation

Qiliang Cai ,

Contributed equally to this work with: Qiliang Cai, Shuvomoy Banerjee

* E-mail: qiliang@fudan.edu.cn (QC); erle@upenn.edu (ESR)

Affiliation MOE&MOH Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
⨯
Shuvomoy Banerjee ,

Contributed equally to this work with: Qiliang Cai, Shuvomoy Banerjee

Affiliation Department of Microbiology and the Tumor Virology Program of Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America
⨯
Amanda Cervini,

Affiliation Department of Microbiology and the Tumor Virology Program of Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America
⨯
Jie Lu,

Affiliation Department of Microbiology and the Tumor Virology Program of Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America
⨯
Andrew D. Hislop,

Affiliation School of Cancer Sciences and Medical Research Council Centre for Immune Regulation, The University of Birmingham, Birmingham, United Kingdom
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Richard Dzeng,

Affiliation Department of Microbiology and the Tumor Virology Program of Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America
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Erle S. Robertson

* E-mail: qiliang@fudan.edu.cn (QC); erle@upenn.edu (ESR)

Affiliation Department of Microbiology and the Tumor Virology Program of Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America
⨯

IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation

Qiliang Cai,
Shuvomoy Banerjee,
Amanda Cervini,
Jie Lu,
Andrew D. Hislop,
Richard Dzeng,
Erle S. Robertson

Published: October 31, 2013
https://doi.org/10.1371/journal.ppat.1003751

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T cells
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Immunoprecipitation
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