Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

Florent Laferrière; Philippe Tixador; Mohammed Moudjou; Jérôme Chapuis; Pierre Sibille; Laetitia Herzog; Fabienne Reine; Emilie Jaumain; Hubert Laude; Human Rezaei; Vincent Béringue

doi:10.1371/journal.ppat.1003702

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Peer-reviewed

Research Article

Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

Florent Laferrière ,

Contributed equally to this work with: Florent Laferrière, Philippe Tixador, Mohammed Moudjou

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Philippe Tixador ,

Contributed equally to this work with: Florent Laferrière, Philippe Tixador, Mohammed Moudjou

Current address: Membrane Traffic and Pathogenesis Unit, Pasteur Institute, Paris, France.

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Mohammed Moudjou ,

Contributed equally to this work with: Florent Laferrière, Philippe Tixador, Mohammed Moudjou

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Jérôme Chapuis,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Pierre Sibille,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Laetitia Herzog,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Fabienne Reine,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Emilie Jaumain,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Hubert Laude,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Human Rezaei,

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯
Vincent Béringue

* E-mail: vincent.beringue@jouy.inra.fr

Affiliation INRA (Institut National de la Recherche Agronomique), UR892, Virologie Immunologie Moléculaires, Jouy-en-Josas, France
⨯

Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

Florent Laferrière,
Philippe Tixador,
Mohammed Moudjou,
Jérôme Chapuis,
Pierre Sibille,
Laetitia Herzog,
Fabienne Reine,
Emilie Jaumain,
Hubert Laude,
Human Rezaei

Published: October 10, 2013
https://doi.org/10.1371/journal.ppat.1003702

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