Modulation of Enhancer Looping and Differential Gene Targeting by Epstein-Barr Virus Transcription Factors Directs Cellular Reprogramming

Michael J. McClellan; C. David Wood; Opeoluwa Ojeniyi; Tim J. Cooper; Aditi Kanhere; Aaron Arvey; Helen M. Webb; Richard D. Palermo; Marie L. Harth-Hertle; Bettina Kempkes; Richard G. Jenner; Michelle J. West

doi:10.1371/journal.ppat.1003636

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Open Access

Peer-reviewed

Research Article

Modulation of Enhancer Looping and Differential Gene Targeting by Epstein-Barr Virus Transcription Factors Directs Cellular Reprogramming

Michael J. McClellan,

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
C. David Wood,

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Opeoluwa Ojeniyi,

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Tim J. Cooper,

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Aditi Kanhere,

Current address: School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

Affiliation MRC Centre for Medical Molecular Virology, Division of Infection and Immunity, Paul O'Gorman Building, University College London, London, United Kingdom
⨯
Aaron Arvey,

Affiliation Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
⨯
Helen M. Webb,

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Richard D. Palermo,

Current address: London Research Institute, Lincoln's Inn Fields Laboratories, London, United Kingdom.

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Marie L. Harth-Hertle,

Affiliation Department of Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany
⨯
Bettina Kempkes,

Affiliation Department of Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany
⨯
Richard G. Jenner,

Affiliation MRC Centre for Medical Molecular Virology, Division of Infection and Immunity, Paul O'Gorman Building, University College London, London, United Kingdom
⨯
Michelle J. West

* E-mail: M.J.West@sussex.ac.uk

Affiliation School of Life Sciences, John Maynard-Smith Building, University of Sussex, Falmer, Brighton, United Kingdom
⨯

Modulation of Enhancer Looping and Differential Gene Targeting by Epstein-Barr Virus Transcription Factors Directs Cellular Reprogramming

Michael J. McClellan,
C. David Wood,
Opeoluwa Ojeniyi,
Tim J. Cooper,
Aditi Kanhere,
Aaron Arvey,
Helen M. Webb,
Richard D. Palermo,
Marie L. Harth-Hertle,
Bettina Kempkes

Published: September 12, 2013
https://doi.org/10.1371/journal.ppat.1003636

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Gene regulation
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