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Open Access
Peer-reviewed
Research Article
An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation
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Stephanie Traub,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Alexandra Nikonova,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Alan Carruthers,
Affiliation MedImmune Ltd, Cambridge, United Kingdom
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Rebecca Dunmore,
Affiliation MedImmune Ltd, Cambridge, United Kingdom
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Katherine A. Vousden,
Affiliation MedImmune Ltd, Cambridge, United Kingdom
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Leila Gogsadze,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Weidong Hao,
Affiliation MedImmune LLC, Gaithersburg, Maryland, United States of America
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Qing Zhu,
Affiliation MedImmune LLC, Gaithersburg, Maryland, United States of America
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Katie Bernard,
Affiliation MedImmune LLC, Gaithersburg, Maryland, United States of America
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Jie Zhu,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Michael Dymond,
Affiliation AstraZeneca, Charnwood, United Kingdom
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Gary R. McLean,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Ross P. Walton,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Nicholas Glanville,
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Alison Humbles,
Affiliation MedImmune LLC, Gaithersburg, Maryland, United States of America
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Musa Khaitov,
Affiliation NRC Institute of Immunology FMBA, Moscow, Russia
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Ted Wells,
Affiliation AstraZeneca, Charnwood, United Kingdom
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Roland Kolbeck,
Affiliation MedImmune LLC, Gaithersburg, Maryland, United States of America
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Andrew J. Leishman,
Affiliation AstraZeneca, Charnwood, United Kingdom
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Matthew A. Sleeman,
Affiliation MedImmune Ltd, Cambridge, United Kingdom
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Nathan W. Bartlett ,
Contributed equally to this work with: Nathan W. Bartlett, Sebastian L. Johnston
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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Sebastian L. Johnston
Contributed equally to this work with: Nathan W. Bartlett, Sebastian L. Johnston
* E-mail: s.johnston@imperial.ac.uk
Affiliation National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, London, United Kingdom
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An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation
- Stephanie Traub,
- Alexandra Nikonova,
- Alan Carruthers,
- Rebecca Dunmore,
- Katherine A. Vousden,
- Leila Gogsadze,
- Weidong Hao,
- Qing Zhu,
- Katie Bernard,
- Jie Zhu
- Published: August 1, 2013
- https://doi.org/10.1371/journal.ppat.1003520