CD40 Activation Rescues Antiviral CD8+ T Cells from PD-1-Mediated Exhaustion

Open Access

Peer-reviewed

Research Article

CD40 Activation Rescues Antiviral CD8⁺ T Cells from PD-1-Mediated Exhaustion

Masanori Isogawa ,

* E-mail: masanori@scripps.edu

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
Josan Chung,

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
Yasuhiro Murata,

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
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Kazuhiro Kakimi,

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯
Francis V. Chisari

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
⨯

T cells
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Cytotoxic T cells
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Mouse models
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Genetically modified animals
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Spleen
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Hepatocytes
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Cell differentiation
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Adoptive transfer
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