miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

Samir Kelada; Praveen Sethupathy; Isobel S. Okoye; Eleni Kistasis; Stephanie Czieso; Sandra D. White; David Chou; Craig Martens; Stacy M. Ricklefs; Kimmo Virtaneva; Dan E. Sturdevant; Stephen F. Porcella; Yasmine Belkaid; Thomas A. Wynn; Mark S. Wilson

doi:10.1371/journal.ppat.1003451

Loading metrics

Open Access

Peer-reviewed

Research Article

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

Samir Kelada ,

Contributed equally to this work with: Samir Kelada, Praveen Sethupathy, Isobel S. Okoye

Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Praveen Sethupathy ,

Contributed equally to this work with: Samir Kelada, Praveen Sethupathy, Isobel S. Okoye

Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Isobel S. Okoye ,

Contributed equally to this work with: Samir Kelada, Praveen Sethupathy, Isobel S. Okoye

Affiliation Division of Molecular Immunology, MRC, National Institute for Medical Research, London, United Kingdom
⨯
Eleni Kistasis,

Affiliation Division of Molecular Immunology, MRC, National Institute for Medical Research, London, United Kingdom
⨯
Stephanie Czieso,

Affiliation Division of Molecular Immunology, MRC, National Institute for Medical Research, London, United Kingdom
⨯
Sandra D. White,

Affiliation Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, Bethesda, Maryland, United States of America
⨯
David Chou,

Affiliation Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, Bethesda, Maryland, United States of America
⨯
Craig Martens,

Affiliation Research Technologies Section, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Stacy M. Ricklefs,

Affiliation Research Technologies Section, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Kimmo Virtaneva,

Affiliation Research Technologies Section, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Dan E. Sturdevant,

Affiliation Research Technologies Section, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Stephen F. Porcella,

Affiliation Research Technologies Section, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Yasmine Belkaid,

Affiliation Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, Bethesda, Maryland, United States of America
⨯
Thomas A. Wynn,

Affiliation Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Disease, Bethesda, Maryland, United States of America
⨯
Mark S. Wilson

* E-mail: mwilson@nimr.mrc.ac.uk

Affiliation Division of Molecular Immunology, MRC, National Institute for Medical Research, London, United Kingdom
⨯

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

Samir Kelada,
Praveen Sethupathy,
Isobel S. Okoye,
Eleni Kistasis,
Stephanie Czieso,
Sandra D. White,
David Chou,
Craig Martens,
Stacy M. Ricklefs,
Kimmo Virtaneva

Published: June 27, 2013
https://doi.org/10.1371/journal.ppat.1003451

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Regulatory T cells
Is the Subject Area "Regulatory T cells" applicable to this article?

Thanks for your feedback.
MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
T helper cells
Is the Subject Area "T helper cells" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.