An Acidic Microenvironment Increases NK Cell Killing of Cryptococcus neoformans and Cryptococcus gattii by Enhancing Perforin Degranulation

• Anowara Islam,

  Affiliation Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

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• Shu Shun Li,

  Affiliation Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

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• Paul Oykhman,

  Affiliation Department of Medical Sciences, University of Calgary, Calgary, Alberta, Canada

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• Martina Timm-McCann,

  Affiliation Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

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• Shaunna M. Huston,

  Affiliation Department of Medical Sciences, University of Calgary, Calgary, Alberta, Canada

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• Danuta Stack,

  Affiliation Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

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• Richard F. Xiang,

  Affiliation Department of Medical Sciences, University of Calgary, Calgary, Alberta, Canada

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• Margaret M. Kelly,

  Affiliation Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada

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• Christopher H. Mody

  * E-mail: cmody@ucalgary.ca

  Affiliations Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada, Department of Internal Medicine, University of Calgary, Calgary, Alberta, Canada

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