Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

Jules A. Nchoutmboube; Ekaterina G. Viktorova; Alison J. Scott; Lauren A. Ford; Zhengtong Pei; Paul A. Watkins; Robert K. Ernst; George A. Belov

doi:10.1371/journal.ppat.1003401

Loading metrics

Open Access

Peer-reviewed

Research Article

Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

Jules A. Nchoutmboube ,

Contributed equally to this work with: Jules A. Nchoutmboube, Ekaterina G. Viktorova

Affiliation Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
⨯
Ekaterina G. Viktorova ,

Contributed equally to this work with: Jules A. Nchoutmboube, Ekaterina G. Viktorova

Affiliation Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
⨯
Alison J. Scott,

Affiliation University of Maryland, School of Dentistry, Baltimore, Maryland, United States of America
⨯
Lauren A. Ford,

Affiliation Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
⨯
Zhengtong Pei,

Current address: Department of Pathology, Saint Barnabas Medical Center, Livingston, New Jersey, United States of America.

Affiliation Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Paul A. Watkins,

Affiliation Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Robert K. Ernst,

Affiliation University of Maryland, School of Dentistry, Baltimore, Maryland, United States of America
⨯
George A. Belov

* E-mail: gbelov@umd.edu

Affiliation Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
⨯

Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

Jules A. Nchoutmboube,
Ekaterina G. Viktorova,
Alison J. Scott,
Lauren A. Ford,
Zhengtong Pei,
Paul A. Watkins,
Robert K. Ernst,
George A. Belov

Published: June 6, 2013
https://doi.org/10.1371/journal.ppat.1003401

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Poliomyelitis
Is the Subject Area "Poliomyelitis" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Fatty acids
Is the Subject Area "Fatty acids" applicable to this article?

Thanks for your feedback.
Poliovirus
Is the Subject Area "Poliovirus" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
HeLa cells
Is the Subject Area "HeLa cells" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.