Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

• Julie L. McAuley ,

  * E-mail: jmcauley@unimelb.edu.au (JLM); Ashley.mansell@monash.edu (AM)

  ¶The research program was led by JLM and AM who are joint senior authors.

  Affiliation Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

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• Michelle D. Tate,

  Affiliation Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia

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• Charley J. MacKenzie-Kludas,

  Affiliation Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

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• Anita Pinar,

  Affiliation Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia

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• Weiguang Zeng,

  Affiliation Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

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• Andrea Stutz,

  Affiliation Institute of Innate Immunity, University Hospitals, University of Bonn, Bonn, Germany

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• Eicke Latz,

  Affiliations Institute of Innate Immunity, University Hospitals, University of Bonn, Bonn, Germany, Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Lorena E. Brown,

  Affiliation Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

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• Ashley Mansell

  * E-mail: jmcauley@unimelb.edu.au (JLM); Ashley.mansell@monash.edu (AM)

  ¶The research program was led by JLM and AM who are joint senior authors.

  Affiliation Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia

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