DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV

Open Access

Peer-reviewed

Research Article

DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4⁺ T Cells Infected with HIV

Mireille Laforge,

Affiliation CNRS FRE 3235, Université Paris Descartes, Paris, France
⨯
Sophie Limou,

Affiliation Chaire de Bioinformatique, Conservatoire National des Arts et Métiers, Paris, France
⨯
Francis Harper,

Current address: UMR8122 CNRS, Institut Gustave Roussy, Villejuif, France.

Affiliation FRE 2937-Génétique Moléculaire et Intégration des Fonctions Cellulaires, Villejuif, France
⨯
Nicoletta Casartelli,

Affiliation Institut Pasteur, Unité Virus et Immunité, Paris, France
⨯
Vasco Rodrigues,

Affiliations CNRS FRE 3235, Université Paris Descartes, Paris, France, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
⨯
Ricardo Silvestre,

Affiliations CNRS FRE 3235, Université Paris Descartes, Paris, France, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
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Houda Haloui,

Affiliation CNRS FRE 3235, Université Paris Descartes, Paris, France
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Jean-Francois Zagury,

Affiliation Chaire de Bioinformatique, Conservatoire National des Arts et Métiers, Paris, France
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Anna Senik,

Affiliation CNRS FRE 3235, Université Paris Descartes, Paris, France
⨯
Jerome Estaquier

* E-mail: estaquier@yahoo.fr

Affiliations CNRS FRE 3235, Université Paris Descartes, Paris, France, Université Laval, Centre de Recherche du CHU de Québec, Québec, Canada
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T cells
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Autophagic cell death
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Small interfering RNA
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Lysosomes
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HIV-1
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HIV infections
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Cell staining
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Apoptosis
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