Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

Tong-Bao Liu; Jong-Chul Kim; Yina Wang; Dena L. Toffaletti; Eliseo Eugenin; John R. Perfect; Kee Jun Kim; Chaoyang Xue

doi:10.1371/journal.ppat.1003247

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Peer-reviewed

Research Article

Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

Tong-Bao Liu ,

Contributed equally to this work with: Tong-Bao Liu, Jong-Chul Kim

Affiliation Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Jong-Chul Kim ,

Contributed equally to this work with: Tong-Bao Liu, Jong-Chul Kim

Affiliation Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Yina Wang,

Affiliations Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America, Tianjin Research Center of Basic Medical Science, Tianjin Medical University, Tianjin, China
⨯
Dena L. Toffaletti,

Affiliation Division of Infectious Disease, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Eliseo Eugenin,

Affiliations Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America, Department of Microbiology and Molecular Genetics, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
John R. Perfect,

Affiliation Division of Infectious Disease, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Kee Jun Kim ,

* E-mail: kkim@kumc.edu (KJK); xuech@umdnj.edu (CX)

Affiliation Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Chaoyang Xue

* E-mail: kkim@kumc.edu (KJK); xuech@umdnj.edu (CX)

Affiliations Public Health Research Institute Center, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America, Department of Microbiology and Molecular Genetics, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯

Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

Tong-Bao Liu,
Jong-Chul Kim,
Yina Wang,
Dena L. Toffaletti,
Eliseo Eugenin,
John R. Perfect,
Kee Jun Kim,
Chaoyang Xue

Published: April 4, 2013
https://doi.org/10.1371/journal.ppat.1003247

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Cryptococcus
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Cryptococcal meningitis
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