An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Reed S. Shabman; Thomas Hoenen; Allison Groseth; Omar Jabado; Jennifer M. Binning; Gaya K. Amarasinghe; Heinz Feldmann; Christopher F. Basler

doi:10.1371/journal.ppat.1003147

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Peer-reviewed

Research Article

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Reed S. Shabman,

Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Thomas Hoenen,

Affiliation Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Allison Groseth,

Affiliation Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Omar Jabado,

Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Jennifer M. Binning,

Affiliations Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Biochemistry Graduate Program, Iowa State University, Ames, Iowa, United States of America
⨯
Gaya K. Amarasinghe,

Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Heinz Feldmann,

Affiliation Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, United States of America
⨯
Christopher F. Basler

* E-mail: chris.basler@mssm.edu

Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
⨯

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Reed S. Shabman,
Thomas Hoenen,
Allison Groseth,
Omar Jabado,
Jennifer M. Binning,
Gaya K. Amarasinghe,
Heinz Feldmann,
Christopher F. Basler

Published: January 31, 2013
https://doi.org/10.1371/journal.ppat.1003147

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