Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 Subset

Cecilia S. Lindestam Arlehamn; Anna Gerasimova; Federico Mele; Ryan Henderson; Justine Swann; Jason A. Greenbaum; Yohan Kim; John Sidney; Eddie A. James; Randy Taplitz; Denise M. McKinney; William W. Kwok; Howard Grey; Federica Sallusto; Bjoern Peters; Alessandro Sette

doi:10.1371/journal.ppat.1003130

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Research Article

Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3⁺CCR6⁺ Th1 Subset

Cecilia S. Lindestam Arlehamn,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Anna Gerasimova,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Federico Mele,

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
⨯
Ryan Henderson,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Justine Swann,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Jason A. Greenbaum,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Yohan Kim,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
John Sidney,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Eddie A. James,

Affiliation Benaroya Research Institute, Seattle, Washington, United States of America
⨯
Randy Taplitz,

Affiliation Antiviral Research Centre, University of California, San Diego, San Diego, California, United States of America
⨯
Denise M. McKinney,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
William W. Kwok,

Affiliation Benaroya Research Institute, Seattle, Washington, United States of America
⨯
Howard Grey,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
Federica Sallusto,

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland
⨯
Bjoern Peters,

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
[ ... ],
Alessandro Sette

* E-mail: alex@liai.org

Affiliation La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
⨯
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Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3⁺CCR6⁺ Th1 Subset

Cecilia S. Lindestam Arlehamn,
Anna Gerasimova,
Federico Mele,
Ryan Henderson,
Justine Swann,
Jason A. Greenbaum,
Yohan Kim,
John Sidney,
Eddie A. James,
Randy Taplitz

Published: January 24, 2013
https://doi.org/10.1371/journal.ppat.1003130

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Mycobacterium tuberculosis
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Islands
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