Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct Ectodomain

Helen M. Wise; Edward C. Hutchinson; Brett W. Jagger; Amanda D. Stuart; Zi H. Kang; Nicole Robb; Louis M. Schwartzman; John C. Kash; Ervin Fodor; Andrew E. Firth; Julia R. Gog; Jeffery K. Taubenberger; Paul Digard

doi:10.1371/journal.ppat.1002998

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Peer-reviewed

Research Article

Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct Ectodomain

Helen M. Wise,

Affiliations Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
⨯
Edward C. Hutchinson,

Current address: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
⨯
Brett W. Jagger,

Affiliations Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom, Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Amanda D. Stuart,

Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
⨯
Zi H. Kang,

Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
⨯
Nicole Robb,

Affiliation Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
⨯
Louis M. Schwartzman,

Affiliation Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
John C. Kash,

Affiliation Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Ervin Fodor,

Affiliation Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
⨯
Andrew E. Firth,

Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
⨯
Julia R. Gog,

Affiliation DAMTP, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
⨯
Jeffery K. Taubenberger,

Affiliation Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Paul Digard

* E-mail: paul.digard@roslin.ed.ac.uk

Affiliations Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
⨯

Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct Ectodomain

Helen M. Wise,
Edward C. Hutchinson,
Brett W. Jagger,
Amanda D. Stuart,
Zi H. Kang,
Nicole Robb,
Louis M. Schwartzman,
John C. Kash,
Ervin Fodor,
Andrew E. Firth

Published: November 1, 2012
https://doi.org/10.1371/journal.ppat.1002998

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