Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation

Erin E. H. Tran; Mario J. Borgnia; Oleg Kuybeda; David M. Schauder; Alberto Bartesaghi; Gabriel A. Frank; Guillermo Sapiro; Jacqueline L. S. Milne; Sriram Subramaniam

doi:10.1371/journal.ppat.1002797

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Open Access

Peer-reviewed

Research Article

Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation

Erin E. H. Tran ,

Contributed equally to this work with: Erin E. H. Tran, Mario J. Borgnia

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Mario J. Borgnia ,

Contributed equally to this work with: Erin E. H. Tran, Mario J. Borgnia

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Oleg Kuybeda,

Current address: National Library of Medicine, NIH, Bethesda, Maryland, United States of America

Affiliation Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
David M. Schauder,

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Alberto Bartesaghi,

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Gabriel A. Frank,

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Guillermo Sapiro,

Affiliation Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Jacqueline L. S. Milne,

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯
Sriram Subramaniam

* E-mail: ss1@nih.gov

Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States of America
⨯

Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation

Erin E. H. Tran,
Mario J. Borgnia,
Oleg Kuybeda,
David M. Schauder,
Alberto Bartesaghi,
Gabriel A. Frank,
Guillermo Sapiro,
Jacqueline L. S. Milne,
Sriram Subramaniam

Published: July 12, 2012
https://doi.org/10.1371/journal.ppat.1002797

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