Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB

Hua Xiang; Yue Feng; Jiawei Wang; Bao Liu; Yeguang Chen; Lei Liu; Xuming Deng; Maojun Yang

doi:10.1371/journal.ppat.1002751

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Open Access

Peer-reviewed

Research Article

Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB

Hua Xiang ,

Contributed equally to this work with: Hua Xiang, Yue Feng

Affiliations Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China, Department of Veterinary Pharmacology, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, China
⨯
Yue Feng ,

Contributed equally to this work with: Hua Xiang, Yue Feng

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Jiawei Wang,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Bao Liu,

Affiliation Department of Vascular Surgery, Peking Union Medical College Hospital, Beijing, China
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Yeguang Chen,

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Lei Liu,

Affiliations Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China, Department of Chemistry, Tsinghua University, Beijing, China
⨯
Xuming Deng ,

* E-mail: xumingdeng@jluhp.edu.cn (XD); maojunyang@tsinghua.edu.cn (MY)

Affiliation Department of Veterinary Pharmacology, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, China
⨯
Maojun Yang

* E-mail: xumingdeng@jluhp.edu.cn (XD); maojunyang@tsinghua.edu.cn (MY)

Affiliation Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯

Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB

Hua Xiang,
Yue Feng,
Jiawei Wang,
Bao Liu,
Yeguang Chen,
Lei Liu,
Xuming Deng,
Maojun Yang

Published: June 14, 2012
https://doi.org/10.1371/journal.ppat.1002751

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