Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the Colon

• Seong Gyu Jeon ,

  Contributed equally to this work with: Seong Gyu Jeon, Hisako Kayama

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Hisako Kayama ,

  Contributed equally to this work with: Seong Gyu Jeon, Hisako Kayama

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Yoshiyasu Ueda,

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Takuya Takahashi,

  Affiliation Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan

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• Takashi Asahara,

  Affiliation Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan

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• Hirokazu Tsuji,

  Affiliation Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan

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• Noriko M. Tsuji,

  Affiliation Age Dimension Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan

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• Hiroshi Kiyono,

  Affiliations Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Division of Mucosal Immunology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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• Ji Su Ma,

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Takashi Kusu,

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Ryu Okumura,

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Hiromitsu Hara,

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

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• Hiroki Yoshida,

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

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• Masahiro Yamamoto,

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Koji Nomoto,

  Affiliation Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan

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•  [ ... ],
• Kiyoshi Takeda

  * E-mail: ktakeda@ongene.med.osaka-u.ac.jp

  Affiliations Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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